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ADENINE CONJUGATE COMPOUNDS AND THEIR USE AS VACCINE ADJUVANTS
专利权人:
Sumitomo Dainippon Pharma Co., Ltd.;AstraZeneca Aktiebolag
发明人:
Hitoshi Ban,Yukihiro Nishio,Padma Malyala,Bilikallahalli K. Muralidhara,Marcus Wong
申请号:
US15763982
公开号:
US20180282334A1
申请日:
2016.09.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present specification relates to adenine conjugate compounds represented by the formula (1), wherein A, L1, L2, X1, R1, R2, R3, and m are as defined herein, or their pharmaceutically acceptable salts. Compounds of formula (1) have immunostimulating properties and may therefore be useful in therapy, for example as vaccine adjuvants. The present specification also relates to a process for preparing adenine conjugate compounds and pharmaceutically acceptable salts thereof, and to pharmaceutical compositions comprising adenine conjugate compounds and their pharmaceutically acceptable salts.
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