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Formulations and dosage forms of oxidized phospholipids
专利权人:
VASCULAR BIOGENICS LTD
发明人:
ALYN MCNAUGHTON,IAN ROBERT WILDING,MASSOUD BAKHSHAEE,NAAMIT SHER,VICTOR M YOUNG
申请号:
BR112014004916
公开号:
BR112014004916A2
申请日:
2012.08.31
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The current disclosure provides pharmaceutical compositions containing an oxidized phospholipid, such as 1-hexadecyl-2-(4′-carboxybutyl)-glycero-3-phosphocholine (VB-201) and a thermosoftening carrier, e.g., a poloxamer. The pharmaceutical compositions may further comprise an anti-adherent agent, such as talc and/or a thixotropic agent. The current disclosure further provides processes for preparing the pharmaceutical compositions. The disclosure further provides capsules containing the pharmaceutical compositions. Uses of such pharmaceutical compositions and capsules in treating inflammatory disorders are also disclosed.
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