The present invention provides compounds of formula (I) that are prodrugs of catecholamine for use in treatment of neurodegenerative diseases and disorders. The present invention also provides pharmaceutical compositions comprising compounds of the invention and methods of treating neurodegenerative or neuropsychiatric diseases and disorders using the compounds of the invention, in particular Parkinson's disease. Accordingly, the present invention relates to compounds of formula (Id) wherein R1 is H and R2 is selected from one of the substituents (i) and (ii) below； or R1 is selected from one of the substituents (i) and (ii) below and R2 is H； or R1 and R2 are both represented by substituent (i) below； or R1 and R2 are both represented by substituent (ii) below； or R1 is substituent (i) and R2 is substituent (ii)； or R1 is substituent (ii) and R2 is substituent (i)； (i) (ii) wherein * indicates the attachment point； and wherein the carbon atom at the attachment point on substituent (i) is in the S-configuration； or a pharmaceutically acceptable salt thereof.
