ARCHIMEDES DEVELOPMENT LIMITED ALBERT EINSTEIN CENTRE
发明人:
WATTS PETER,CHENG YU-HUI,WATTS Peter,CHENG Yu-Hui
申请号：
SI200830875
公开号：
SI2214640T1
申请日:
2008.11.10
申请国别(地区):
SI
年份:
2013
代理人:
摘要：
The present invention provides a liquid aqueous formulation for the intranasal administration of apomorphine, which comprises: (a) at least about 15 mg/ml of apomorphine； and (b) a solubilising agent selected from (i) at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer)； (ii) at least one cyclodextrin； and (iii) at least one cyclodextrin together with chitosan. The formulations of the invention can be used in the treatment/management of Parkinson's disease.
