PROBLEM TO BE SOLVED: To provide a drug delivery system capable of spatially and temporally releasing an agent with high accuracy.SOLUTION: A drug delivery system comprises: a liposome which has a molecule intercalated between lipid double membranes and includes an agent and a light irradiation device which induces a double resonance absorption process by simultaneously irradiating the molecule with light with having at least two different wavelength, and heats and destabilizes the lipid double membranes at a temperature equal to or higher than a phase transition temperature of a membrane structure of the lipid double film so as to release the agent to the outside of the liposome.COPYRIGHT: (C)2015,JPO&INPIT【課題】空間的及び時間的に高精度で薬剤を放出することができるドラッグデリバリーシステムを提供する。【解決手段】本発明に係るドラッグデリバリーシステムは、脂質二重膜の間にインターカレートした分子を有し、薬剤を内包するリポソームと、分子に対して少なくとも2種以上の異なる波長の光を同時照射することで二重共鳴吸収過程を誘導して、脂質二重膜の膜構造の相転移温度以上に脂質二重膜を加熱し、不安定化させ、薬剤をリポソームの外部に放出させる光照射装置と、を含む。【選択図】図1
