CALIFORNIA INSTITUTE OF TECHNOLOGY;LILI YANG;PIN WANG;DAVID BALTIMORE
发明人:
PIN WANG,LILI YANG,DAVID BALTIMORE
申请号:
IL19663909
公开号:
IL196639A
申请日:
2009.01.21
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.