A phototherapy patch is disclosed and which includes: an adhesive layer and having a first surface and an opposite second surface a pharmaceutical drug layer and disposed ON the first surface of the adhesive layer and a spontaneous emission layer and disposed over the pharmaceutical drug layer and capable of emitting therapeutic light by light illumination or a chemical reaction. Accordingly, the phototherapy patch according to the present invention has no POWER supply disposed therein and thereby is suitable to be manufactured as a particularly thin and thus inconspicuous device.