Robin Steigerwald,Christine Meisinger-Henschel,Eva Felder
申请号:
US13131586
公开号:
US08772023B2
申请日:
2009.11.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to a promoter selected from a group of nucleic acids consisting of (a) a nucleic acid having the nucleotide sequence of SEQ ID NO:1 (b) a nucleic acid having a nucleotide sequence derived from SEQ ID NO:1, wherein not more than 10 nucleotides have been added, deleted, substituted and/or inverted from the nucleic acid of SEQ ID NO:1 and (c) a nucleic acid sequence having at least 70% identity with the nucleic acid of (a) wherein the promoter has a length of up to and including 27 nucleotides and wherein the promoter according to options (b) and (c) exhibits at least the 70% of the promoter activity of SEQ ID NO:1 as measured by the amount of recombinant protein produced.