President and Fellows of Harvard College;John Guilinger;David Liu;Vikram Pattanayak
发明人:
Liu, David R.,Guilinger, John Paul,Pattanayak, Vikram
申请号:
AU2012333134
公开号:
AU2012333134A1
申请日:
2012.07.22
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Engineered nucleases (e.g., zinc finger nucleases (ZFNs), transcriptional activator-like effector nucleases (TALENs), and others) are promising tools for genome manipulation and determining off-target cleavage sites of these enzymes is of great interest. We developed an