A method for treating rheumatoid arthritis in a Subject that has been previously treated with methotrexate, leflunomide, sulfasalazine and / or Hydroxychloroquine, which comprises administering to the subject an effective amount of sarilumab； and Pharmaceutical composition comprising sarilumab and a member of the Grup Or what is methotrexate, leflunomide, sulfasalazine and Hydroxychloroquine.
HUANG, XIAOHONG,JASSON, MARTINE,MARKS, VANESSA,RADIN, ALLEN
申请号：
CL2014000926
公开号：
CL2014000926A1
申请日:
2014.04.11
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The present invention provides compositions and methods of treating and improving the symptoms of rheumatoid arthritis using an antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R) with a DMARD.<；p>；USO DE UN ANTICUERPO ANTI-IL-6R EN COMBINACIÓ；N CON METOTREXATO PARA PREPARAR UN MEDICAMENTO Ú；TIL PARA TRATAR LA ARTRITIS REUMATOIDE.<；/p>；
