Kevin Michael SHORT,Maria de los Angeles ESTIARTE-MARTINEZ,David Ben KITA,Timothy Philip SHIAU
申请号:
US15553540
公开号:
US20180237421A1
申请日:
2016.02.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin and/or kallikrein, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which diseases or disorders are amenable to treatment or prevention by the inhibition of thrombin and/or kallikrein.