The invention relates to medicine and can be used in surgery, including cosmetic surgery, for example for treating trophic and persistent ulcers, pressure sores, burns, scars, etc., and also for the purpose of rejuvenating biological tissues, inter alia skin, in different locations. Proposed is a method for the renewal of biological tissues with the restoration of the functional properties, characteristics and structure thereof, in which the tissues are subjected to a predetermined degree of mechanical traumatization through the creation, in given areas, of at least one region of interference between acoustic waves emanating from at least two sources and propagating in the tissues which are to be renewed, with the possibility of the subsequent natural regeneration of the biological tissues concerned in the aforesaid areas. Also proposed are various embodiments of a device for the implementation of the above method. In order to achieve the result of the renewal of different biological tissues situated at different depths, areas of micro trauma are created without thermal effects, i.e. without the evaporation or coagulation of all of the overlying tissues, i.e. the regeneration of the tissues occurs without the growth of fibrotic cells, thus making it possible to speak of actual, rather than merely visible, rejuvenation.Linvention concerne la médecine et peut sutiliser en chirurgie, y compris en chirurgie cosmétique, par exemple, pour traiter des ulcères trophiques et difficilement guérissables, des escarres, des brûlures, des balafres, etc., ainsi que à des fins de rajeunissement de cellules biologiques, y compris de la peau, de localisations diverses. On propose un procédé de renouvellement des tissus biologiques avec rétablissement de leurs fonctionnalités, de leurs caractéristiques et de leur structure dans ce procédé, les tissus sont soumis à des lésions mécaniques à des degrés différents par la création dans des zones déterminées dau moins une zone dinterférenc
