Peptide comprising 7-17 contiguous amino acids and hexamer, where the peptide does not contain tumor necrosis factor (TNF)-receptor-binding activity and is cyclized, is new. Peptide comprising 7-17 contiguous amino acids and hexamer of formula (TX1EX2X3E), where the peptide does not contain tumor necrosis factor (TNF)-receptor-binding activity and is cyclized, is new. X1, X2, X3 : natural or unnatural amino acid. N.B.: T and E are not defined. An independent claim is included for a composition comprising the peptide, which is formulated in the composition for administration to the human, and carrier. ACTIVITY : None given. MECHANISM OF ACTION : None given.