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NOVEL ANTI-PLATELET COMPOUND ADDITION SALT
专利权人:
GUANGZHOU HEERSHI PHARMA DEVELOPMENT CO.; LTD.
发明人:
YAN, XIAOJING
申请号:
EP12771534
公开号:
EP2698371A4
申请日:
2012.04.09
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to a use of haloid acid salt and sulfonate of a compound of formula I and a salt of the compound of formula I in preparation of medicament for preventing or treating diseases caused by thrombosis or embolism. The present invention provides acid addition salts, especially haloid acid and sulfonic acid addition salts of a compound of formula I having high inhibition effect on platelet aggregation, and preparation method of the same, a medicament comprising the same, and a use and/or method for preventing or treating diseases caused by thrombosis or embolism. The present invention discloses the hydrohalic acid and sulfonic acid addition salts of the compound of general formula I, their preparation process, and their use in manufacture of a medicament for treating or preventing thrombus or embolism. The salts of the present invention are more stable that the free compound pre se, possess good oral absorption and excellent inhibitory effect on platelet aggregation and stability with high potential to be an anti-thrombotic agent.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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