Yi Chen;Ashoke Bhattacharjee;Joyce A. Sutcliffe;Deping Wang;Edward C. Sherer;Joel A. Goldberg;Yanming Du;Zoltan F. Kanyo;Yusheng Wu;Joseph A. Ippolito;Rongliang Lou;Adegboyega K. Oyelere;Jay J. Farmer
发明人:
Jay J. Farmer,Ashoke Bhattacharjee,Yi Chen,Joel A. Goldberg,Joseph A. Ippolito,Zoltan F. Kanyo,Rongliang Lou,Adegboyega K. Oyelere,Edward C. Sherer,Joyce A. Sutcliffe,Deping Wang,Yusheng Wu,Yanming Du
申请号:
US10590782
公开号:
US08202843B2
申请日:
2005.02.25
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides macrocyclic compounds useful as therapeutic agents of the formula:or a pharmaceutically acceptable salt, ester, N-oxide, or prodrug thereof, wherein T, R1, R2, R3, D, E, F, and G are as defined herein. More particularly, these compounds are useful as anti-infective, antiproliferative, anti-inflammatory and prokinetic agents.