An apparatus comprising a conduit clamping device with a closing mechanism for closing and opening passage of fluid or air in a flexible conduit is disclosed. The apparatus comprises a movable arm or disk that is connected to a manipulation arm or a knob a conduit in form of a tube, that is laid flat against an abutment or protrusion and a guide structure that constrains the movable arm or disk between the guide structure and the tube and being designed such that movement of the arm or disk will control the compression of the tube.