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ANTI-HUMAN UROTHELIAL CARCINOMA OF SUPERCRITICAL CARBON DIOXIDE EXTRACT OF CINNAMOMUM SUBAVENIUM, AND THE PREPARATION PROCESS AND USES
专利权人:
A-MEI HUANG;CHUNG-YI CHEN;PEI-JUNG LIEN;JIH-HENG LI;CHIUNG-HUI LIU
发明人:
JIH-HENG LI,A-MEI HUANG,CHUNG-YI CHEN,PEI-JUNG LIEN,CHIUNG-HUI LIU
申请号:
US13426136
公开号:
US20130122110A1
申请日:
2012.03.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
What is disclosed in the invention is a preparation method of a supercritical Cinnamomum subavenium extract, which is made from the material, the dried stem of C. subavenium. The extract is obtained by extracting C. subavenium which is pulverized as particles with supercritical carbon dioxide fluid. The C. subavenium extract or its active ingredient, subamolide A, can be used to inhibit the growth of human urothelial carcinoma cell lines. In addition, the C. subavenium extract (or subamolide A) is able to synergistically inhibit the growth of human urothelial carcinoma cell lines with cisplatin (CDDP) or gemcitabine (Gem). Therefore, the C. subavenium extract (or subamolide A) can be an anticancer drug alone, or forms a pharmaceutical composition with CDDP (or Gem) to treat with cancers in respect of urinary system.
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