SASAKI, Ken,WILLIAMSON, Vanessa, Jane,ARAUJO, Alberto de,WALCZYK, Ewa
申请号:
MEP4612
公开号:
ME01366B
申请日:
2004.11.22
申请国别(地区):
ME
年份:
2013
代理人:
摘要:
GLP-2 peptides and analogs thereof are produced in high yield and with desired, authentic termini by isolation from a GLP-2 peptide multimer in which at least two units of GLP-2 peptide are coupled through a linker that presents an N-terminal acid cleavage site and a C-terminal enzyme cleavage site. In a specific embodiment, [Gly2]hGLP-2 is produced from a multimeric precursor comprising 2-30 units thereof.