A method is disclosed. The method can comprise obtaining a first staple cartridge and obtaining a second staple cartridge, wherein the first staple cartridge and the second staple cartridge comprise the same length and the same width. The method can further comprise inserting the first staple cartridge into a channel comprising a keyed profile, wherein complete insertion of the first staple cartridge into the channel is prevented by the keyed profile. Additionally, the method can comprise inserting the second staple cartridge into the channel, wherein complete insertion of the second staple cartridge into the channel is permitted by the keyed profile.