PROBLEM TO BE SOLVED: To provide a combination of organic compounds, for example, pharmaceutical active compounds.SOLUTION: A pharmaceutical combination comprising an mTOR inhibitor and a Raf kinase inhibitor and showing synergistic activity is provided. A use of the combination is also provided.【課題】本発明は、有機化合物、例えば薬学的活性化合物の組合せに関する。【解決方法】mTOR阻害剤およびRafキナーゼ阻害剤を含む、相乗的活性を示す医薬組合せ剤、ならびにその使用の提供。【選択図】なし