REIMANN, HANSJOERG,SCHIRMBECK, REINHOLD, ALOIS,LINDBLAD, ERIK, B.
申请号：
DK03720397
公开号：
DK1490100T3
申请日:
2003.03.28
申请国别(地区):
DK
年份:
2012
代理人:
摘要：
The present invention relates to a combined DNA/Protein antigen vaccine composition which includes nucleic acid molecules and a mineral-based, negatively charged adjuvant, so as to enhance the immunogenicity of the DNA vaccine efficiently, enhancing not only plasmid DNA vaccines but also providing a novel strategy for immunogenic, multivalent combined protein/DNA vaccine delivery. Preferred adjuvants are aluminum or calcium salts, in particular aluminum phosphate.
