A mechanism for increasing resistance to Enterobacteriaceae infection is described. Additionally genetic markers for identifying traits associated with resistance to Enterobacteriaceae are also described. Thus the invention provides methods and compositions for the production of animals which exhibit increased resistance to Enterobacteriaceae infection. The invention further provides methods and compositions for marker assisted breeding to identify animals resistant to Enterobacteriaceae infection. The invention allows for cattle production with lower susceptibility to Enterobacteriaceae infection.
