#$%^&*AU2014386720A120160121.pdf#####3 6 ABSTRACT A uric acid-lowering agent containing, as an active ingredient, a tyrosinecontaining cyclic dipeptide selected from the group consisting of cyclotryptoph anyltyrosine, cycloseryltyrosine, cycloprolyltyrosine, cyclotyrosylglycine. cyclotyrosyltyrosine, cyclophenyialaniyltyrosine, cycloleucyltyrosine cycolysyltyrosine, cyclohistidyftyrosine, cycl oalanyityrosine, cycloglutamyityrosine, cyclovalyityrosine, cycloisoleucyltyros in. cyclothreonyltyrosin e, cycloaspartyltyrosine, 10 cycloasparaginyltyrosine, cycloglutaminyevtyrosine cycloarginyltyrosine. cyclonethionyityrosine, and cyclotyrosyicysteine, or a salt thereof. The uric acid-lowering agent of the present invention has an excellent action of lowering a uric acid level, and the uric acid-lowering agent is tiseful i, for example, prevention or treatment of hyperuricemia, gout or the like.
