Use of mazindol (I) for the preparation of a drug for the preventive and/or curative treatment of the attention deficit hyperactivity disorder (ADHD) or at least one of these symptoms in a patient. An independent claim is included for a composition comprising (I) and excipients for the preventive and/or curative treatment of ADHD or any of its symptoms. ACTIVITY : Nootropic; Tranquilizer; Hypnotic; Muscular-Gen; Neuroprotective; Antiparkinsonian; Metabolic. MECHANISM OF ACTION : Dopamine inhibitor; Noradrenalin reuptake inhibitor. No biological data given.