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An improved process for the preparation of blonanserin
专利权人:
发明人:
NAGESWARA RAO KARUSALA,BHAUSAHEB CHAVHAN,RADHA KRISHNA SINGAMSETTY,SUDARSHAN RAO KOTHA KONDA,SUNIL KUNAMNENI
申请号:
IN1406/CHE/2012
公开号:
IN2012CH01406A
申请日:
2012.04.09
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to an improved process for the preparation of 4-(4-Fluorophenyl)-5,6,7,8,9,10-hexahydro cyclooctane [b] pyridine-(lH)-ketone comprising the steps of hydrolyzing 4-Fluorobenzoyl acetonitrile in presence of an acid reacting with Cyclooctanone and isolating 4-(4-Fluorophenyl)-5,6,7,8,9,10-hexahydro cyclooctane [b] pyridine-(lH)-ketone. The present invention also relates to further conversion 4-(4- Fluorophenyl)-5,6,7,8,9,10-hexahydro cyclooctane [b] pyridine-(lH)-ketone into Blonanserin. The present invention also provides, process for the preparation of Blonanserin Hydrchloride and further conversion of Blonanserin Hydrchloride to pure Blonanserin.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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