3-[(4-fenilperidin-1-il) carbonill) propylene glycol inhibitor HDM2; pharmaceuticals synthesis including UNOI; and compounds used in the production of effective drugs for different types of cancer, such as Vejig A, from Rion Colon and others
WANG YAOLIN,MA YAO,BOGEN STEPHANE L,LAHUE BRIAN ROBERT,NAIR LATHA G,SHIZUKA MANAMI,VOSS MATTHEW ERNST,KIROVA SNO
申请号:
CL2012000949
公开号:
CL2012000949A1
申请日:
2012.04.13
申请国别(地区):
CL
年份:
2012
代理人:
摘要:
Compounds derived from [3 - (4 - fenilpiperidin - triazin-1-yl] piperidine substituted carbonill) that modulate the activity of p53; Pharmaceutical Composition and its use in the preparation of a Medicament for the TreatmentSelected: cancer, bladder cancer, Breast, endometrial, Lung, myelogenous leukemia, melanoma, among others.Compuestos derivados de 3-[(4-fenilpiperidin-1-il)carbonill]piperidina sustituida que modulan la actividad de P53; composición farmacéutica; y sus usos en la preparación de un medicamento para el tratamiento de cáncer, seleccionado de cáncer de vejiga, de mama, endometrio, pulmón, leucemias mielógenas, melanoma, entre otros.