An injection syringe, comprising a syringe cylinder, a plunger rod that is inserted therein and connected to a stopper by way of a coupling part, and a module that is provided in the proximal end of the syringe cylinder and comprises a cannula (4), which is mounted in a cannula holder (3) received in a guiding sleeve, and further a sealing insert (1) for the fluid-tight closure of the proximal end of the syringe cylinder and a protective cap for protecting the cannula (4), wherein the protective cap on the inner circumference has ribs extending in the axial direction, which engage in corresponding grooves of the driving part (5) for a rotary drive thereof, and wherein in the sealing insert (1) a hollow space is formed, which is closed on the proximal side and on the distal side transitions into an opening, by way of which a tip of the coupling part can be coupled to the hollow space.
