The invention relates to tumour therapy. In one aspect, the present invention relates to conjugates of an amatoxin and a target-binding moiety, e.g. an antibody, connected by certain linkages, which are useful in the treatment of cancer and other disorders and diseases. In a further aspect the invention relates to pharmaceutical compositions comprising such conjugates.本發明係關於腫瘤療法。在一態樣中,本發明係關於藉由某些鏈接連結之毒傘肽(amatoxin)及靶結合部分(例如抗體)之偶聯物,其可用於治療癌症及其他病症及疾病。在另一態樣中,本發明係關於包括該等偶聯物之醫藥組合物。
