David TELLERS,Steven L. COLLETTI,Vadim DUDKIN,Jeffrey AARONSON,Aaron MOMOSE,Thomas Joseph TUCKER,Yu YUAN,Kathleen B. CALATI,Lu TIAN,Rubina G. PARMAR,Anthony W. SHAW,Weimin WANG,Rachel Anne STORR,Marin
申请号：
US15481942
公开号：
US20170306324A1
申请日:
2017.04.07
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed herein is a modular composition comprising 1) an oligonucleotide 2) one or more tetraGalNAc ligands of Formula (I), which may be the same or different optionally, 3) one or more linkers, which may be the same or different 4) one or more peptides independently selected from Table 3, which may be the same or different and optionally, 5) one or more targeting ligands, solubilizing agents, pharmacokinetics enhancing agents, lipids, and/or masking agents.
