The present invention relates to a compound having a structure in which isotretinoin and a peptide are covalently linked, and an antibacterial, anti-inflammatory or antioxidant pharmaceutical composition or cosmetic composition containing the same. The compound having a structure in which isotretinoin and the peptide of the present invention are covalently linked is not only excellent in physiological activity such as antibacterial, anti-inflammatory, or antioxidant action, but also excellent in properties such as solubility in water. , May be usefully used in various fields such as pharmaceuticals and cosmetics.本発明は、イソトレチノインとペプチドが共有結合で連結された構造を有する化合物、及びこれを含む抗菌、抗炎症又は抗酸化用の薬学的組成物又は化粧料組成物に関する。本発明のイソトレチノインとペプチドが共有結合で連結された構造を有する化合物は、抗菌、抗炎症、又は抗酸化作用のような生理活性に優れるだけではなく、水での溶解度などの特性に優れるため、医薬品又は化粧品などの多様な分野に有用に用いられてよい。