In a method and tomosynthesis apparatus for combined dual-energy mammography and tomosynthesis imaging of a predetermined volume of an examination subject, while contrast agent is flowing through the volume, an x-ray source is set to radiate x-rays at low and high radiation energy. A pre-shot of the volume is obtained with the high radiation energy, and recording parameters for high-energy images, low-energy images, and low-energy tomosynthesis scans are obtained from the pre-shot. A high-energy image is then obtained, followed by operating the x-ray source at a low energy, and a low-energy tomosynthesis scan of the volume is executed using the recording parameters, and a two-dimensional low-energy image of the volume is generated during the low-energy tomosynthesis scan.
