PROBLEM TO BE SOLVED: To provide a nucleic acid capable of inhibiting the expression of MEX3B gene in a cell, an MEX3B gene expression inhibitor comprising such a nucleic acid, a method for inhibiting the expression of MEX3B gene, and a prophylactic or therapeutic agent for disease caused by MEX3B gene expression.SOLUTION: According to the present invention, there is provided a nucleic acid comprising a sequence complementary to an oligonucleotide containing at least 10 consecutive nucleotides in an intron of the MEX3B gene and inhibiting the expression of the MEX3B gene.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】細胞内において、MEX3B遺伝子の発現を抑制することができる核酸、上記核酸を含むMEX3B遺伝子発現抑制剤、MEX3B遺伝子発現を抑制する方法及びMEX3B遺伝子発現に起因する疾病の予防又は治療剤を提供すること。【解決手段】MEX3B遺伝子のイントロン中の連続する少なくとも10ヌクレオチドを含むオリゴヌクレオチドに相補的な配列を有し、MEX3B遺伝子の発現を抑制する核酸。【選択図】図1
