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FORMULATIONS COMPRISING TRIPTAN COMPOUNDS
专利权人:
DR. REDDY'S LABORATORIES LIMITED
发明人:
Rajesh GANDHI,Sreekanth MANIKONDA,Arun JANA,Sameer Shrinivas KUNTE
申请号:
US15434814
公开号:
US20170157091A1
申请日:
2017.02.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides a pharmaceutical composition for intranasal administration comprising a salt of sumatriptan or a physiologically acceptable solvate thereof, an alkyl glycoside or saccharide alkyl ester and optionally at least one pharmaceutically acceptable excipient, wherein the said composition provides Tmax value of less than 30 minutes upon said administration. Other aspects and embodiments are contemplated and described.The invention also provides a pharmaceutical composition for intranasal administration comprising a triptan, a pharmaceutically acceptable vehicle and a mucosal permeation enhancer, wherein upon said administration said composition provides a Tmax substantially equivalent to subcutaneous administration of said triptan. Other aspects and embodiments are contemplated and described.
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