The Arizona Board of Regents on Behalf of the University of Arizona
发明人:
Meredith Hay,John Konhilas,Robin L. Polt,Evan Jones
申请号：
US15134073
公开号：
US09670251B2
申请日:
2016.04.20
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides oligopeptides, in particular, Ang-(1-7) derivatives, and methods for using and producing the same. In one particular embodiment, oligopeptides of the invention have higher blood-brain barrier penetration and/or in vivo half-life compared to the native Ang-(1-7), thereby allowing oligopeptides of the invention to be used in a wide variety of clinical applications including in treatment of cognitive dysfunction and/of impairment.
