Elena Casale,Francesco Casuscelli,Claudio Dalvit,Paolo Polucci,Fabio Zuccotto
申请号:
US13394255
公开号:
US20120184546A1
申请日:
2010.09.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to [1,2,4]triazolo[1,5-c]pyrimidine derivatives of formula (I) which inhibit the activity of Heat Shock Protein Hsp90. The compounds of the invention are therefore useful in treating proliferative diseases such as cancer and neurodegenerative diseases. The present invention also provides processes for preparing these compounds, methods of treating diseases and the pharmaceutical compositions comprising these compounds.