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Pyrimidine tricyclic enone derivatives for inhibition of RORgamma and other uses
专利权人:
Inc.;Reata Pharmaceuticals
发明人:
Jiang, Xin,Bender, Christopher F.,Visnick, Melean,Hotema, Martha R.,Sheldon, Zachary S.,Lee, Chitase,Caprathe, Bradley William,Bolton, Gary,Kornberg, Brian
申请号:
AU2017377852
公开号:
AU2017377852A1
申请日:
2017.12.16
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Disclosed herein are compounds of the formulas: as well as analogs thereof, wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used to inhibit RORγ and/or reduce the expression of IL-17. Also provided are methods of administering compounds and composition provided herein to a patient in need thereof, for example, for the treatment or prevention of diseases or disorders associated with inflammation or autoimmune disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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