A method for isolating a potential anomaly in imaging data is disclosed, the method comprising providing a set of at least one given anomaly property representative of a given anomaly providing a anomaly property identifier for identifying each of the at least one given anomaly property in the imaging data, isolating a first zone having a first property and a group of at least one other zone, each of the at least one other zone having a corresponding property different than the first property in the imaging data, and resulting from the isolation of a first zone and a group of at least one other zone, providing a transition zone selected from a group consisting of: a closed zone separating the first zone and the group of at least one other zone and a closed zone extending in one of the first zone and the group of at least one other zone applying the anomaly property identifier for identifying each of the at least one given anomaly property on at least the transition zone for providing a computed indication for a selected zone, the selected zone being at least the transition zone determining if the computed indication for the selected zone is concording with each of the at least one given anomaly property and if the computed indication for the selected zone is concording, assigning an indication of potential anomaly candidate zone to the selected zone to thereby isolate the potential anomaly.