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TRPV1 antagonists including dihydroxy substituent and uses thereof
专利权人:
Purdue Pharma L.P.;Shionogi & Co., Ltd.
发明人:
Shigeru Ando,Noriyuki Kurose,Laykea Tafesse
申请号:
US15018493
公开号:
US09630959B2
申请日:
2016.02.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The disclosure relates to Compounds of Formula (I)and pharmaceutically acceptable derivatives thereof, where R1, R4, R8, R9, and m are as defined herein, compositions comprising an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, pain associated with osteoarthritis, osteoarthritis, UI, an ulcer, IBD, and IBS, comprising administering to an animal in need thereof an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof.
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