John G. Wise,Pia D. Vogel,Frances K. Brewer,Courtney A. Follit
申请号:
US14598022
公开号:
US09561227B2
申请日:
2015.01.15
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug resistant cells; administering to the subject a pharmaceutically effective amount of an inhibitor compound, and contacting one or more drug resistant cells with the inhibitor compound to reduce the export of the inhibitor compound from the one or more drug resistant tumor cells and to block the transport of drug(s) from the one or more drug resistant cells.