Combination of a BACE inhibitor and an antibody or antigen-binding fragment for the treatment of a disorder associated with the accumulation of amyloid beta

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专利权人:

AstraZeneca AB

发明人:

Johnston, Conor

申请号：

AU2017232277

公开号：

AU2017232277A1

申请日:

2017.03.15

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present disclosure provides for methods for treating a subject having a disease or disorder associated with the accumulation of amyloid beta, comprising administering to the subject a BACE inhibitor and an antibody or antigen-binding fragment that binds to amyloid beta n-42. In some embodiments, the disease or disorder is Alzheimer's Disease.

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