ACIDES HYDROXAMIQUES HETEROCYCLIQUES COMME INHIBITEURS DE PROTEINE DESACETYLASE ET INHIBITEURS DOUBLES DE PROTEINE KINASE-PROTEINE DESACETYLASE, ET LEURS PROCEDES D'UTILISATION
THE REGENTS OF THE UNIVERSITY OF COLORADO; A BODY CORPORATE
发明人:
LIU, XUEDONG,ZHANG, GAN,CHAN, DANIEL CHUEN-FONG,PISCOPIO, ANTHONY D.
申请号:
CA2949163
公开号:
CA2949163A1
申请日:
2015.05.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to novel hydroxamic acids which are specific histone deacetylase (HDAC) inhibitors and/or TTK/Mpsl kinase inhibitors, including pharmaceutically acceptable salts thereof, which are useful for modulating HDAC and/or TTK/Mpsl kinase activity, pharmaceutical compositions comprising these compounds, and processes for their preparation.