NUCLEIC ACID CONSTRUCT CONTAINING NUCLEIC ACID DERIVED FROM GENOTYPE 1B HCV GENOME, HCV GENOME-REPLICATING CELLS TRANSFECTED WITH SAME, AND METHOD FOR PRODUCING INFECTIOUS HCV PARTICLES

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专利权人:

发明人:

申请号：

EP12765083.6

公开号：

EP2692861A1

申请日:

2012.03.30

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

A subgenomic replicon RNA (nucleic acid) having an excellent autonomously replicating ability and a fullgenomic replicon RNA (nucleic acid) having an excellent autonomously replicating ability and infectious HCV particle-producing ability, each derived from a novel HCV of genotype 1b, are provided. Particularly, a subgenomic replicon RNA (nucleic acid) and a fullgenomic replicon RNA (nucleic acid), each derived from an HCV genome of the NC1strain which is a novel HCV genotype 1b isolated from a patient with acute severe hepatitis C, are provided.

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