The Board of Trustees of the University of Illinois
发明人:
Komarova, Yulia A.,Saqib, Uzma,Vogel, Stephen M.,Malik, Asrar B.
申请号:
AU2012271781
公开号:
AU2012271781C1
申请日:
2012.06.13
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Provided herein are peptide inhibitors of the interaction between End Binding Protein 3 (EB3) and Inositol 1,4,5-Trisphosphate Receptor Type 3 (IP3R3). Also provided are methods and materials for treating lung injury, including acute lung injury, which may include hyperpermeability of lung vessels, vascular leakage, the development of edema, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion.