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Method for preventing the crystallization of pharmaceuticals in a polymer film
专利权人:
LTS Lohmann Therapie-Systeme AG
发明人:
Johannes Josef Leonhard,Walter Mueller
申请号:
US14056025
公开号:
US09408809B2
申请日:
2013.10.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to a method for preventing the crystallization of a pharmaceutical in a polymer film, wherein the solvent-containing coating compound, which comprises a matrix-forming polymer or polymer mixture and at least one pharmaceutical and is spread to produce the polymer film, is temporarily dried at temperatures that is at least 10° C. above the melting temperature of the pharmaceutical contained in the coating compound. The maximum temperature is thus higher than that which is required for mere drying and obviates the need for an additional, time-consuming and expensive work step.
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