9-[4-(3-CHLOR-2-FLUOR-PHENYLAMINO)-7-METHOXY-QUINAZOLIN-6-YLOXY]-1,4-DIAZA-SPIRO[5.5]UNDECAN-5-ONE DIMALEATE, USE THEREOF AS A DRUG, AND PRODUCTION THEREOF
The present invention relates to a compound of formula (I), which has valuable pharmacological properties, particularly an inhibiting effect on signal transduction mediated by tyrosine kinases, processes for stereoselectively preparing these compounds, particularly pharmaceutical formulations suitable for inhalation and their use for the treatment of diseases, particularly tumoral diseases, benign prostatic hyperplasia and diseases of the lungs and airways.유용한 약리학적 특성을 갖는, 특히 티로신 키나제에 의해 매개된 신호 전달에 대해 억제 효과를 갖는 화학식 I의 화합물, 상기 화합물의 입체선택적 제조방법, 특히 흡입에 적합한 약제학적 제형, 및 질환, 특히, 종양 질환, 전립선 비대증 및 폐와 기도의 질환의 치료를 위한 이들의 용도에 관한 것이다.화학식 I