The present invention relates to a plant cultivation factory system which prevents external contaminants from entering a factory. The plant cultivation factory system comprises: a cultivation tray including culture soil or a culture medium where a plant is planted a cultivation building unit having a plurality of cultivation levels divided by horizontal partition walls vertically arranged at regular intervals, and a plurality of cultivation rooms divided by vertical partition walls horizontally arranged at regular intervals on each of the plurality of cultivation levels to allow the cultivation tray to be aligned and arranged to cultivate plants a transport unit having a first unmanned transport vehicle moved along the interior of the plurality of cultivation rooms and a second unmanned transport vehicle moved along a first transport path arranged on each of the plurality of cultivation levels to load the first unmanned transport vehicle on an upper surface thereof to be connected to the plurality of cultivation rooms to transport the cultivation tray into or out of the cultivation rooms by the first unmanned transport vehicle loaded and unloaded from the second unmanned transport vehicle stopped at an entrance of the cultivation rooms and a lifting unit having a second transport path vertically arranged on one side of the cultivation building unit to be connected to an entrance of a transport path arranged on each of the plurality of cultivation levels, and a transport cart to allow the second unmanned transport vehicle with the first unmanned transport vehicle loaded thereon to enter the same and exit from the same to lift and lower the transport cart to be positioned on any one among the plurality of cultivation levels along the second transport path.식물재배 공장시스템을 제공한다. 식물이 식재되는 배양토 또는 배양액을 포함하는 재배트레이 수직방향으로 일정간격을 두고 구비되는 수평격벽에 의해서 분할구획되는 복수개의 재배층을 갖추고, 상기 복수개의 재배층마다 수평방향으로 일정간격을 두고 구되는 수직격벽에 의해서 분할구획되어 상기 재배트레이가 정렬배치되는 복수개의 재배실을 갖추어 식물재배가 이루어지는 재배건물부 상기 복수개의 재배실