Oliver Plettenburg;Katrin Lorenz;Matthias Loehn;Olivier Duclos;Sandrine Biscarrat
发明人:
Oliver Plettenburg,Katrin Lorenz,Matthias Loehn,Olivier Duclos,Sandrine Biscarrat
申请号：
US13000202
公开号：
US08524737B2
申请日:
2009.06.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to bi- and polycyclic substituted isoquinoline and isoquinolinones of the formula (I) wherein R1 to R12 are as defined in the application useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
