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PERSONALIZED TREATMENT OF CANCER USING FGFR INHIBITORS
专利权人:
MOMENTOUS IP VENTURES LLC
发明人:
THOMAS, ROMAN K.,MALCHER, FLORIAN
申请号:
CA2862530
公开号:
CA2862530A1
申请日:
2014.09.05
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to a method for predicting the responsiveness ofcancer cells to FGFR inhibitors, which comprises the evaluation of the statusofFGFR1 gene and the status of MYC. A kit useful for carrying out the method isalsoprovided. In addition, a method of treating cancer such as lung cancer is alsoprovided which includes determining the status of FGFR1 gene and the status ofMYCgene, and administering to the cancer patient an FGFR inhibitor if the tumortissue orcells exhibit an increased expression or amplification of the FGFR1 gene, aswell asan increased expression or amplification of the MYC gene.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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