Stephen Hoge,William Issa,Edward J. Miracco,Jennifer Nelson,Amy E. Rabideau,Gabor Butora
申请号：
US16001786
公开号：
US10653712B2
申请日:
2018.06.06
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to improved RNA compositions for use in therapeutic applications. The RNA compositions are particularly suited for use in human therapeutic application (e.g., in RNA therapeutics). The RNA compositions are made by improved processes, in particular, improved in vitro-transcription (IVT) processes. The invention also relates to methods for producing and purifying RNA (e.g, therapeutic RNAs), as well as methods for using the RNA compositions and therapeutic applications thereof.
