COMPOSÉS 3- (PHÉNYL)-N- (4-PHÉNOXYBENZYL) -1,2,4-OXADIAZOLE-5-CARBOXAMIDE POUR LA PRISE EN CHARGE DE MALADIES MÉDIÉES PAR LA PROTÉINE CFTR

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专利权人:

Emory University

发明人:

MCCARTY, Nael,CUI, Guiying

申请号：

EP16804126

公开号：

EP3302466A4

申请日:

2016.05.27

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

This disclosure relates to methods of treating or preventing cystic fibrosis transmembrane conductance regulator (CFTR) mediated diseases such as cystic fibrosis, chronic obstructive pulmonary disease, chronic pancreatitis, chronic bronchitis, asthma, mucus formation, comprising administering an effective amount of a 3-(phenyl)-N-(4-phenoxybenzyl)-1,2,4-oxa-diazole-5-carboxamide compound, salt, or derivative thereof to a subject in need thereof. In certain embodiments, the 2-amino-N-benzylidene-acetohydrazide compound is 3-(3,5-dibromo-4-hydroxyphenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide.

来源网站：

中国工程科技知识中心

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